Thursday, March 03, 2005
This Day:

According to Purdue University scientists, a newly discovered plant protein complex that apparently switches on plants' growth machinery, has opened a scientific toolbox to learn about both plant and animal development. Results are published in the February issue of the journal The Plant Cell.
The protein complex (ARP2/3) controls the production of actin filaments, which are necessary for cellular growth and movement. These filaments organize the inside of the cell and allow it to grow, and also determine where certain structures in a cell are positioned and how plants respond to gravity and light. Similar structures (myosin), exist in animal muscles.

Hair-like Trichomes on leaves (Courtesy: Purdue)
The research showed that a another protein called DISTORTED3 (DIS3) turns on ARP2/3, which in turn triggers formation of new, growing actin filaments(e.g. in trichomes, which are hair-like structures on leaves). Because some genes have survived through time as multicellular life evolved, they have been conserved in both plants and animals. So, some of the plant proteins that comprise the ARP2/3 and the WAVE complexes are interchangeable with proteins in animals, for example, DIS3 has two ends that are common in both plant and animal proteins!
Scientists are now studying these protein complexes to study biochemical reactions (in both plants and animals). This process eventually may allow researchers to design plants better able to protect themselves from insects and disease.

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6 Comments:

At March 04, 2005 5:54 AM, Blogger Sray said...
It might certainly be possible. Remember that reptiles and amphibians are able to regrow body parts. We can also regenerate albeit at a more restricted level (healing wounds, growing new muscle fibres, etc.).

But one has to watch out for cancers, though!
 
At March 04, 2005 12:39 PM, Blogger Ostrich said...
Super site!!! Scientific thought in nice measured doses for Amateurs with interest! Excellent! A spoonful of science makes the medicine go down, in the most delightful way!

Incidentally, how does this combine or aid or challenge stem cell research?
 
At March 04, 2005 12:56 PM, Blogger Sray said...
Thanks Ostrich :-). BTW: how did you come up with that nick? Your site suggests anything but!

Understanding the biochemical reactions that underlie all organisms is always a plus. Once we are able to decipher how a muscle for example, works, it should be possible to reverse/prevent muscle degenerating diseases (like Parkinsons, ALS).

Stem-cells are used since they can *become* any cell in the body, and thereby generate the necessary proteins/hormones (at least in some cases, when the goal is not to create a new organ, but to correct an hormonal/neuronal problem). If we can directly manufacture and inject the proteins, that would be an interesting alternative to using stem cells.
 
At March 04, 2005 12:59 PM, Blogger Wayne Smallman said...
It's recently been discovered that the Anaconda has the ability to increase the size and strength of its heart.

This is done prior to ingesting food -- which is a non-trivial task for most snakes since they swallow their prey in one.

The process is [obviously] reversible.

Also, there is a plant -- whose name I do not know -- that has hemoglobin just like animals.

So if you cut it, you will see blood...
 
At March 04, 2005 1:30 PM, Blogger Sray said...
Some other organisms (some worms similar to echinoderms) have haemoglobin.

Plant hemoglobins are called leg-hemoglobins, and they perform a similar function (plants breathe oxygen too.. just that they produce more than they breathe in).

All the following are organometallic or metalloprotein compounds, very similar in structure.

Chlorophyll (plants, has magnesium)
Haeomoglobin (animals, iron)
Hemocyanin (crustaceans/molluscs, blue)
Chromagen (Sea-squirts, vanadium)
Cyanocobalamine (Vitamin B-12, Cobalt)

Interesting how nature works!
 
At March 04, 2005 7:26 PM, Blogger Wayne Smallman said...
An interesting idea, but you'd probably still suffer from hardened arteries and other heart-related illnesses...
 

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