Humans need almost 8 hours of sleep per day. Some people enjoy sleeping (like me!), but when you think about it, sleeping for a third of your lifetime sounds like a awful waste of time :(. Now scientists at the University of Wisconsin have discovered a possible mutation in a single gene in the fruit-fly (Drosophila Melanogaster) genome, that allows the flies to get 30% less sleep than their normal counterparts!
The finding is important, as it might point to possible mutations in the human genome that might help us control sleep, and also shed light on human sleep needs. This fruit-fly gene has a counterpart in animal (and human) genome; so such a mutation might just be possible in humans too :).

Fruit Fly (Courtesy: University of Guelph) Chiara Cirelli and colleagues discovered that flies with one particular gene variant, dubbed minisleep, needed only 3 or 4 hours’ rest per day, compared to 10 to 12 hours for a normal fly. The most interesting part: the flies, despite all the sleep deprivation, showed no sign of impairment.
They were also able to go without any sleep for much longer periods of time. The minisleep mutation is in a gene called Shaker, which codes for a protein that forms part of an ion channel in nerve cells. The same protein is found in mammals, and might serve the same function as in flies.
If we were able to conquer sleep, it might be helpful in a lot of ways. In particular, it will help those among us who always feel sleepy (including some of the readers here :D:D, you know who you are!), and also help people working odd or late hours, and of course the military might be really interested.
The finding is important, as it might point to possible mutations in the human genome that might help us control sleep, and also shed light on human sleep needs. This fruit-fly gene has a counterpart in animal (and human) genome; so such a mutation might just be possible in humans too :).

Fruit Fly (Courtesy: University of Guelph)
They were also able to go without any sleep for much longer periods of time. The minisleep mutation is in a gene called Shaker, which codes for a protein that forms part of an ion channel in nerve cells. The same protein is found in mammals, and might serve the same function as in flies.
If we were able to conquer sleep, it might be helpful in a lot of ways. In particular, it will help those among us who always feel sleepy (including some of the readers here :D:D, you know who you are!), and also help people working odd or late hours, and of course the military might be really interested.
21 Comments:
Hmmmmm. I understand some scientists believe sleep is a necessary 'reset device' the brain uses to sort thoughts out and re-assign pathways (from memory). If there was no sleep they theorise that people would actually go insane over time.
Have you heard of a "russian sleep" unit? I think it's just sci-fi at the moment (and every day more sci-fi things are becoming reality) but it's a device to 'force' REM sleep. If you combined the two advances that may work!
"Russian Sleep" machine thing is interesting :))... but I dont know if the two (the machine, and the minisleep mutation) can be combined.
By the way, there are mammals who sleep much much less than we do, and are still quite active. The question is: why do we sleep so much? Why did we evolve like this?
i just find it so funny and at the same time so useful :D
whats the russian sleep machine? any link on it?
Russian Sleep Machine: I am not sure it works... it might be partly a hype/legend. For more info, click here.
Well, perhaps I shouldnt keep postponing work till the last minute before deadlines :)).
I used to think I was unfortunate not to have inherited that trait. But now I think my subconscious world is equally valuable. Whatever my subconscience needs to work its magic is OK with me! I value my sleep time for more than just rest.
onkroes: Yes, sleep deprivation causes insanity. One of my kids was colicky, so I know!!
Deb, another interesting thing is: as people grow older, they need less and less sleep. But they are still quite active! Why cant that happen when we are younger? That is a mystery to me.
Good one :)):)).
Yes.
Your short-term memory is moved into long-term memory during sleep.
Your dreams are essentially a visual representation of your brain filing your thoughts and experiences.
Lack of sleep is one of the reasons why people hallucinate; their brains are trying to do an emerging back-up!
As I understand it, the brain needs a chemical called Seratonin [among others], but it's only produced during sleep when much of the brain is switched off or in low power mode.
This chemical is needed for muscle functions, that's why you ache when you're tired.
This is where Sray either corrects or fills out the details...
I remember watching a television program about narcolepsy, now that is weird. Just nodding off without warning.
It seems that the default state of the brain is at rest. Being awake requires effort. So with the average narcoleptic, the power switch is faulty and keeps breaking and going back to 'off' when it should be 'on'.
Not good!
Abt. serotonin. It is one of the major neuro-transmitters in the brain. Decreased levels of serotonin can cause body ache, and depression. Serotonin is given as an antidote for depression, and is also one reason why we go to sleep when on anti-depressants. Conversely, without serotonin, our thinking abilities are often impaired.
Gindy: I am sure experiments have been done with soldiers. It is not hard to stay awake. The problem is: people become zombies, and you dont want zombie soldiers! What the mutation might do is allow you to be alert, and aware of what is going on around you.
But one side-effect for the fruit-flies, that I just found out in a BBC article, was that the mutated flies (with less sleep) died earlier than others :-(:-(.
Yes, I saw that one.
The soldier was non other than B-movie star Tony Todd...
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